Editorial Cardiovascular risks and outcomes: ethnic variations in hypertensive patients
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چکیده
Epidemiological studies of international variations in disease incidence have helped to generate and test hypotheses about the relative importance of genetic, environmental, social, and cultural factors in causing cardiovascular diseases. Studies of racial and ethnic variation within countries have also contributed in advancing such understanding. Indian, Bangladeshi, and Pakistani people born on the Indian subcontinent (henceforth called South Asian) but living in England and Wales have a 40–50% higher mortality from coronary heart disease than the population average. 3 The prevailing hypothesis explaining this excess is the insulin resistance hypothesis. Coronary heart disease, paradoxically, is comparatively low among Afro-Caribbeans, who share with South Asians a high prevalence of insulin resistance. Another paradox concerns hypertension, one of the major coronary risk factors, as ethnic variations in blood pressure do not parallel variations in coronary heart disease. Prevalence of hypertension among the AfroCaribbean and African populations is high, but their risk of death from coronary heart disease is low. 5 There is conflicting evidence over whether hypertension is more common in South Asian groups. One study found diastolic blood pressure among South Asian (predominantly Punjabi) men in Glasgow was higher than in the general population, but this was not so for South Asian women, or for systolic blood pressure in South Asian men. South Asian groups in Newcastle, particularly Bangladeshis, were found to have lower blood pressure than Europeans. Paradoxically Bangladeshis have the highest mortality from coronary heart disease. These and many other paradoxes require cohort studies in order to be resolved; therefore the recent article by Khattar and colleagues is of special interest.
منابع مشابه
Cardiovascular risks and outcomes: ethnic variations in hypertensive patients.
Epidemiological studies of international variations in disease incidence have helped to generate and test hypotheses about the relative importance of genetic, environmental, social, and cultural factors in causing cardiovascular diseases. Studies of racial and ethnic variation within countries have also contributed in advancing such understanding. Indian, Bangladeshi, and Pakistani people born ...
متن کاملBHOPAL and SUSHMITA SENGUPTA - WIEBE variations in hypertensive patients Cardiovascular risks
متن کامل
Effects of L-citrulline on Oxidative Stress Markers Following High Intensity Interval Exercises in Hypertensive Patients
Background and Objectives: High blood pressure affects nearly 30% of adults. Inactivity and low intake of antioxidants are associated with increased risks of high blood pressure and cardiovascular diseases. High intensity interval exercise increases blood pressure and oxidative stress. The purpose of this study was to investigate effects of L-citrulline consumption on oxidative stress and antio...
متن کاملA comparative study between citanest and mepivacaine on high blood pressure in hypertensive patients
A comparative study between citanest and mepivacaine on high blood pressure in hypertensive patients Dr. SM. Ghoreyshian * - Dr. A. Teymouri** - Dr. M. Mansouri** *- Assistant professor of Oral Maxillofacial Surgery Dept.- Faculty of Dentistry- Isfahan University of Medical Sciences. ** - Dentist. Background and aim: Selection the proper local anestheteic drug in dental procedures especiall...
متن کاملEthnic variations in lipid-lowering in response to a statin (EVIREST): a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT).
BACKGROUND Statins improve lipid profiles and reduce cardiovascular morbidity and mortality but there are few data on their relative effects in different ethnic groups. METHODS We used data from the randomised, placebo-controlled Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA) to conduct a prespecified comparison of the lipid-lowering efficacy of statin therapy among ...
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تاریخ انتشار 2000